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结构式 货号 产品名称 CAS号
Infliximab 结构式
BCP20310 英夫利昔单抗 170277-31-3
Infliximab is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases.
Belnacasan 结构式
BCP02893 贝尔纳卡桑 273404-37-8
Belnacasan (VX-765) is an orally absorbed prodrug of VRT-043198, which exhibits potent inhibition against ICE/caspase-1 and caspase-4 with Ki of 0.8 nM and less than 0.6 nM, respectively.
BMS-202 结构式
BCP16068 BMS-202 1675203-84-5
BMS-202 is an inhibitor of the PD-1/PD-L1 protein/protein interaction, mainly used for cancer treatment.
Deshydroxyethoxy Ticagrelor 结构式
BCP14589 替格瑞洛杂质G 220347-05-7
Deshydroxyethoxy Ticagrelor analog of Ticagrelor an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.
Fexaramine 结构式
BCP15784 Fexaramine 574013-66-4
Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds.
Ponatinib 结构式
BCP02037 泊那替尼 943319-70-8
Ponatinib (AP24534) is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, 2, 1.5, 2.2, 1.1, 1and 0.24 nM for native pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosphorylation and LYN.
Luminespib 结构式
BCP01827 Luminespib 747412-49-3
Luminespib is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively.
Ostarine 结构式
BCP02391 Ostarine 841205-47-8
Ostarine (MK-2866) is an androgen receptor modulator (SARM) with an ED50 of 0.44 mg/day.
CB-839 结构式
BCP28287 CB-839 1439399-58-2
CB-839 is a potent and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC), and with IC50s of 23 nM and 28 nM in kidney and brain, respectively.
Mirdametinib 结构式
BCP01841 Mirdametinib 391210-10-9
Mirdametinib, also known as PD-0325901, is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity.
GDC-0941 结构式
BCP01714 GDC-0941 957054-30-7
Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity.
Orantinib 结构式
BCP01984 Orantinib 252916-29-3
TSU-68 (SU6668)is a novel multiple receptor tyrosine kinase inhibitor with IC50 of 2.1 μM, 8 nM and 1.2 μM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively.
Lapatinib 结构式
BCP01874 拉帕替尼 231277-92-2
Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.
Camptothecin 结构式
BCP02857 喜树碱 7689-03-4
Camptothecin is a potent DNA enzyme topoisomerase I inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
LY294002 结构式
BCP00195 LY294002 154447-36-6
LY294002 is a highly selective inhibitor of phosphatidylinositol 3-kinase.
Rapamycin 结构式
BCP01404 雷帕霉素 53123-88-9
Rapamycin is antifungal and immunosuppressant and specific inhibitor of mTOR.
Cabazitaxel 结构式
BCP27641 卡巴他赛 183133-96-2
A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor.
Plerixafor 结构式
BCP02337 普乐沙福 110078-46-1
Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
Empagliflozin 结构式
BCP06962 依帕列净 864070-44-0
Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes.
CL2A-SN-38 结构式
BCP32728 CL2A-SN-38 1279680-68-0
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).
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