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AKT

结构式 货号 产品名称 CAS号
TAS-117 结构式
BCP41128 TAS-117 1402602-94-1
TAS-117 is a PKB/Akt inhibitor potentially for the treatment of solid tumors.
Merck-22-6 结构式
BCP36078 Merck-22-6 612847-42-4
Merck-22-6 is an allosteric dual Akt1, Akt2 inhibitor.
Urolithin B 结构式
BCP35736 尿石素B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
Recilisib sodium 结构式
BCP35048 Recilisib sodium 922139-31-9
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
E-Guggulsterone 结构式
BCP34834 孕二烯二酮 39025-24-6
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii.
(Z)-Guggulsterone 结构式
BCP07472 孕二烯二酮 39025-23-5
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Miransertib HCl 结构式
BCP25709 ARQ092盐酸盐 1313883-00-9
Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
Ipatasertib dihydrochloride 结构式
BCP23821 帕他色替双盐酸盐 1396257-94-5
Ipatasertib dihydrochloride is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Recilisib 结构式
BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
AT7867 dihydrochloride 结构式
BCP30936 AT7867 dihydrochloride 1431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
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