首页   >  
Angiogenesis/Protein Tyrosine Kinase
  >  
FAK

所有产品分类

所有产品

信号通路

研究领域

天然产物

抗体

多肽

催化剂

杂质对照品

医药中间体

基础原料

FAK

结构式 货号 产品名称 CAS号
PF-562271HCl 结构式
BCP42811 PF-562271 HCl 939791-41-0
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.
Y15 tetrahydrochloride 结构式
BCP27854 Y15 tetrahydrochloride 4506-66-5
Y15 is a potent and specific inhibitor of focal adhesion kinase (FAK) that inhibits its autophosphorylation activity, decreases the viability of cancer cells, and blocks tumor growth.
BI-4464 结构式
BCP30859 BI-4464 1227948-02-8
BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
PF 4618433 结构式
BCP29572 PF 4618433 1166393-85-6
PF 4618433 is an inhibitor of proline-rich tyrosine kinase 2 (PYK2) and focal adhesion kinase (FAK).
Y 11 结构式
BCP28812 Y 11 1086639-59-9
Y11 is a small molecule inhibitor targeting Y397 site of FAK.
Repotrectinib 结构式
BCP19778 洛普替尼 1802220-02-5
TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 5.3 nM, 1.01 nM, 1.26 nM and 1.08 nM for SRC, WT ALK, ALK G1202R and ALK L1196M, respectively.
CEP-37440 结构式
BCP13227 CEP-37440 1391712-60-9
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
PF-562271 benzenesulfonate 结构式
BCP14770 PF 562271 苯磺酸盐 939791-38-5
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 13 nM, and has > 100-fold selectivity against other protein kinases, except for some CDKs.
GSK-2256098 结构式
BCP18311 GSK-2256098 1224887-10-8
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.
Defactinib 结构式
BCP11299 地法替尼 1073154-85-4
Defactinib is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
12下一页共 19 条记录 1 / 2 页 
2853530910