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PKC

结构式 货号 产品名称 CAS号
Bisindolylmaleimide VIII acetate 结构式
BCP43574 Bisindolylmaleimide VIII acetate 138516-31-1
Bisindolylmaleimide VIII acetate is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC.
Bisindolylmaleimide IV 结构式
BCP43512 双吲哚马来酰亚胺 IV 119139-23-0
Bisindolylmaleimide IV is an inhibitor of pyruvate phosphate dikinase (PPDK).
D-erythro-Sphingosine HCl 结构式
BCP40404 D-erythro-Sphingosine HCl 2637-72-5
D-erythro-Sphingosine is an inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
Phorbol 12,13-dibutyrate 结构式
BCP38374 Phorbol 12,13-dibutyrate 37558-16-0
Phorbol 12,13-dibutyrate is a PKC activator and a potent skin tumor promoter.
CMPD101 结构式
BCP37871 CMPD101 865608-11-3
CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. CMPD101 can be used for the study of heart failure.
A-3 Hydrochloride 结构式
BCP37347 赤霉酸盐酸盐 78957-85-4
A-3 hydrochloride is an inhibitor of PKA, PKC, and casein kinase I and II, and MLCK.
Hispidin 结构式
BCP34507 牛奶树碱 555-55-5
Hispidin, a PKC inhibitor and a phenolic compound from Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties.
VTX-27 结构式
BCP32667 VTX-27 1321924-70-2
VTX-27 is a novel potent and selective PKCθ inhibitor.
4alpha-PDD 结构式
BCP32104 4alpha-PDD 27536-56-7
4alpha-PDD is a negative control for Phorbol-12,13-didecanoate (PDD) and Phorbol-12-myristate-13-acetate (PMA). Though it is inactive for signaling through PKC, 4alpha-PDD has been shown to activate transient receptor potential vanilloid 4 (TRPV4) channels.
Bisindoylmaleimide X 结构式
BCP25395 Bisindoylmaleimide X 1241725-89-2
Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC).
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