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Integrase

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Integrase

结构式 货号 产品名称 CAS号
BMS-538203 结构式
BCP10394 BMS-538203 543730-41-2
BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent.
Bictegravir 结构式
BCP25703 比卡格韦 1611493-60-7
Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
Bictegravir Sodium 结构式
BCP20910 Bictegravir Sodium 1807988-02-8
Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile.
GSK1265744 结构式
BCP08631 GSK1265744 1051375-10-0
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
Cabotegravir Sodium 结构式
BCP24687 卡博特韦钠盐 1051375-13-3
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
Dolutegravir sodium 结构式
BCP11890 度鲁特韦钠盐 1051375-19-9
Dolutegravir sodium salt is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Raltegravir 结构式
BCP01394 雷特格韦 518048-05-0
Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
Dolutegravir 结构式
BCP02329 度鲁特韦 1051375-16-6
Dolutegravir is an integrase inhibitor being developed for the treatment of human immunodeficiency virus (HIV)-1 infection by GlaxoSmithKline (GSK) on behalf of Shionogi-ViiV Healthcare LLC.
Raltegravir potassium 结构式
BCP01757 雷特格韦钾盐 871038-72-1
Raltegravir Potassium Salt is a potent human immunodeficiency virus (HIV) integrase inhibitor
Elvitegravir 结构式
BCP01801 埃替拉韦 697761-98-1
Elvitegravir is a human immunodeficiency virus integrase inhibitor with EC50 of 0.7, 2.8 and 1.4 for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD.
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