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Prostaglandin Receptor

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Prostaglandin Receptor

结构式 货号 产品名称 CAS号
Prostaglandin G2 结构式
BCP42810 前列腺素 G2 51982-36-6
Prostaglandin G2 is a prostaglandins G.
Pizuglanstat 结构式
BCP42640 Pizuglanstat 1244967-98-3
Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.
BAY 1316957 结构式
BCP40674 BAY 1316957 1613264-40-6
BAY-1316957 is a highly potent, selective, orally available human prostaglandin E2 receptor subtype 4 (hEP4-R) antagonist (IC50= 15.3 nM ) with excellent drug metabolism and pharmacokinetics properties.
U-46619 结构式
BCP39866 U-46619 56985-40-1
U46619 is a PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM).
BGC-20-1531 结构式
BCP37893 BGC-20-1531 1186532-61-5
BGC-20-1531 is a EP4 antagonist for the treatment of acute migraine.
ONO-8130 结构式
BCP37875 ONO-8130 459841-96-4
ONO-8130 is an orally available EP1 receptor antagonist.
DG-041 结构式
BCP35669 DG-041 861238-35-9
DG 041 inhibits PGE2 facilitation of platelet aggregation in vitro and ex vivo. Displays good plasma and metabolic stability.
TG4-155 结构式
BCP25837 TG4-155 1164462-05-8
TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. It blocks the induced expression of inflammatory markers in microglial cells.
AM-211 结构式
BCP32870 AM-211 1175526-27-8
AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
AH 23848 calcium salt 结构式
BCP26022 AH 23848 calcium salt 81496-19-7
AH 23848 calcium salt is a dual antagonist of TP1 and EP4 receptors.
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