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Sigma Receptor

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Sigma Receptor

结构式 货号 产品名称 CAS号
SR 31747 结构式
BCP35688 SR 31747 132173-07-0
SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase.
BD 1047 结构式
BCP33959 BD 1047 138356-20-4
BD-1047 is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.
Cutamesine 结构式
BCP32724 Cutamesine 165377-43-5
Cutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4±1.9 nM); 100-fold less affinity for the sigma 2 receptor.
BD1063 dhydrochloride 结构式
BCP31637 BD1063 dhydrochloride 206996-13-6
BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
CT-1812 结构式
BCP30368 CT-1812 1802632-22-9
CT-1812 is a sigma-2 (σ-2) receptor antagonist.
4-IBP 结构式
BCP29985 4-IBP 155798-08-6
4-IBP combines high affinity for σ1 and moderate affinity for σ2 sites. Centrally active following systemic administration in vivo.
PB28 dihydrochloride 结构式
BCP25164 PB28 dihydrochloride 172906-90-0
PB-28 is an agonist of the sigma-2 receptor.
AVex-73 hydrochloride 结构式
BCP24794 AVex-73 hydrochloride 195615-84-0
AVex-73 hydrochloride is a Sigma-1 Receptor agonist with an IC50 of 860 nM.
AVex-73 结构式
BCP23552 AVex-73 195615-83-9
AVex-73 acts as a muscarinic receptor and a moderate sigma1 receptor agonist.
S1RA 结构式
BCP08990 S1RA 878141-96-9
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).
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