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结构式 货号 产品名称 CAS号
JNJ-54166060 结构式
BCP44118 JNJ-54166060 1627900-42-8
JNJ-54166060 is a potent P2X7 antagonist.
GS-9901 结构式
BCP44115 GS-9901 1640247-87-5
GS-9901 is a potent, orally active and highly selective inhibitor of PI3Kδ (PI3Kdelta IC50 = 1.0nM, HWB delta EC50 = 1.5 nM; CLpr hHep = 0.05 L/h/kg.).
CHR-3996 结构式
BCP44113 CHR-3996 1235859-13-8
CHR-3996 is an orally bioavailable, second-generation hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
AZD-7451 结构式
BCP44112 AZD-7451 1079274-94-4
AZD7451 is a tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity
RN983 结构式
BCP44110 RN983 1423129-83-2
RN983 is a selective BTK enzyme inhibitor.
Iodine (131I) Derlotuximab Biotin 结构式
BCP44109 碘[131I]美妥昔单抗 340013-96-9
PF-06459988 结构式
BCP44108 PF-06459988 1428774-45-1
PF-06459988 is an orally available, small molecule, third-generation, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant (EGFRm) forms with potential antineoplastic activity.
Panulisib 结构式
BCP44105 Panulisib 1356033-60-7
Panulisib is an orally bioavailable inhibitor of phosphoinositide 3-kinase (PI3K), mammalian target of rapamycin (mTOR), activin receptor-like kinase 1 (ALK-1) and DNA-dependent protein kinase (DNA-PK), with potential anti-angiogenic and antineoplastic activities.
Encorafenib 结构式
BCP44104 Encorafenib 1269440-29-0
Encorafenib is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells.
Bomedemstat ditosylate 结构式
BCP44102 Bomedemstat ditosylate 1990504-72-7
Bomedemstat is a lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity.
Pulrodemstat 结构式
BCP44101 Pulrodemstat 1821307-10-1
Pulrodemstat is a potent and orally active LSD1 inhibitor. CC-90011 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively. CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell lines, and antitumor efficacy in patient-derived xenograft (PDX) SCLC models.
Gartisertib 结构式
BCP44100 Gartisertib 1613191-99-3
Gartisertib is an ATP-competitive, orally active, and selective inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase with Ki of < 150 pM. VX-803 (M4344) potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (P-Chk1) phosphorylation with IC50 of 8 nM. VX-803 (M4344) exhibits potential antineoplastic activity.
c-Fms-IN-12 结构式
BCP44099 c-Fms-IN-12 1313407-95-2
c-Fms-IN-12 is a c-Fms inhibitor.
BIIB068 结构式
BCP44097 BIIB068 1798787-27-5
BIIB068 is a potent, selective, reversible and orally active BTK inhibitor.
1-Hydroxy Bilastine 结构式
BCP44096 1'-羟基比拉斯汀 1638785-23-5
Debio-0123 结构式
BCP44092 Debio-0123 2243882-74-6
Debio 0123 is a Wee1 kinase inhibitor.
Afimetoran 结构式
BCP44088 Afimetoran 2171019-55-7
Afimetoran is a toll-like receptor antagonist and immunomodulator.
Xanthosine 结构式
BCP44083 黄嘌呤核苷 146-80-5
Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine can increase mammary stem cell population and milk production in cattle and goats.
2-Isopropyladamantan-2-yl acrylate 结构式
BCP44056 2-异丙基-2-金刚烷醇丙烯酸酯 251564-67-7
Dynarrestin 结构式
BCP44170 Dynarrestin 2222768-84-3
Dynarrestin is a dynein inhibitor. Inhibits hedgehog signaling in vitro (IC50 = 0.22 μM). Exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport. Inhibits tumor cell proliferation in a mouse medulloblastoma model.
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