Lumacaftor

  • Chemical Properties
CAS No. 936727-05-8 Cat. No. BCP02305
Name Lumacaftor
Synonyms VX809;VX-809;VX 809; VRT-826809; VRT 826809; VRT826809;
Formula C24H18F2N2O5 M. Wt 452.41
  • Biological Activity
Description Lumacaftor, also known as VX-809, is a potent CFTR corrector, many be useful for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation. Cystic fibrosis (CF) is a genetic disorder that causes multiorgan morbidity and premature death, most commonly from pulmonary dysfunction.
Pathways Ion Channel/Membrane Transporter 
Targets CFTR 

Structure

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