Org 25935 hydrochloride
| CAS No. | 949588-40-3 | Cat. No. | BCP27717 |
| Name | Org 25935 hydrochloride | ||
| Synonyms | Org-25935; SCH-900435; Org 25935; SCH 900435; Org 25935; SCH 900435; | ||
| Formula | C21H25NO3.HCl | M. Wt | 375.9 |
| Description | Org-25935 is a potent, selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 100 nM; shows negligible action on GlyT2; produces a robust and dose-dependent decrease in EtOH consumption in rats, reduces compulsive relapse-like drinking without the development of tolerance. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | GlyT | ||
Structure
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