Elagolix

  • Chemical Properties
CAS No. 834153-87-6 Cat. No. BCP08827
Name Elagolix
Synonyms NBI56418; NBI-56418; NBI 56418; ABT-620; ABT 620; ABT620;
Formula C32H30F5N3O5 M. Wt 631.59
  • Biological Activity
Description Elagolix, also known as NBI56418 and ABT-620, is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. Elagolix is believed to have its effect by altering the level of pituitary GnRH suppression and, as a result, titrating circulating estrogen levels.
Pathways GPCR/G Protein 
Targets GnRH Receptor 

Structure

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