依那普利
| CAS号 | 75847-73-3 | 货号 | BCP09039 |
| 中文名 | 依那普利 | ||
| 英文名 | Enalapril | ||
| 中文别名 | |||
| 英文别名 | Gadopril; MK 421; MK-421; MK421; | ||
| 分子式 | C20H28N2O5 | 分子量 | 376.45 |
| 生物活性 | Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. | ||
| 信号通路 | Protease/Metabolic Enzyme Hormone Pathay | ||
| 靶 点 | RAAS/ACE | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！