Diclofenac
| CAS No. | 15307-86-5 | Cat. No. | BCP09087 |
| Name | Diclofenac | ||
| Synonyms | Diclofenac acid; 1-(2,6-Dichlorophenyl)-2-indolinone; | ||
| Formula | C14H11Cl2NO2 | M. Wt | 296.15 |
| Description | Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. It is supplied as or contained in medications under a variety of trade names. As a nonsteroidal anti-inflammatory drug (NSAID), Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins. This agent also may inhibit COX-2-mediated tumor angiogenesis. When inhibiting COX-2, Diclofenac may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. This agent may be more active against COX-2 than several other carboxylic acid-containing NSAIDs. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | COX | ||
Structure
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