BIO-acetoxiMe
| CAS号 | 667463-85-6 | 货号 | BCP27976 |
| 中文名 | BIO-acetoxiMe | ||
| 英文名 | BIO-acetoxime | ||
| 中文别名 | |||
| 英文别名 | BIA; GSK-3 Inhibitor X;6-bromoindirubin-3'-acetoxime; | ||
| 分子式 | C18H12BrN3O3 | 分子量 | 398.22 |
| 生物活性 | BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. Also, BIO-Acetoxime induces Wnt signaling and inhibits CD8+ T cell effector differentiation. BIO-acetoxime is a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus. BIO-Acetoxime protects cells from varicella infection. BIO-acetoxime may suppress viral gene expression and protect oral epithelial cells from HSV-1 infection. | ||
| 信号通路 | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| 靶 点 | GSK3 | ||
结构式
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