10074-G5
| CAS No. | 413611-93-5 | Cat. No. | BCP09223 |
| Name | 10074-G5 | ||
| Synonyms | 10074G5;10074 G5; | ||
| Formula | C18H12N4O3 | M. Wt | 332.31 |
| Description | 10074-G5 is a c-Myc Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4, specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM) most likely due to the fact that 10074-G5 binds to a different region of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | c Myc | ||
Structure
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