琥珀酸普卡必利
| CAS号 | 179474-85-2 | 货号 | BCP09320 |
| 中文名 | 琥珀酸普卡必利 | ||
| 英文名 | Prucalopride Succinate | ||
| 中文别名 | |||
| 英文别名 | R-108512; R 108512; R108512; | ||
| 分子式 | C18H26ClN3O3.C4H6O4 | 分子量 | 485.96 |
| 生物活性 | Prucalopride succinate is a selective, high affinity 5-HT4 receptor agonist with pKi of 8.6/8.1 for 5-HT4a/4b.Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4) receptor agonist with enterokinetic activities. Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation. Prucalopride was approved for use in Europe in 2009. | ||
| 上下游产品 | 179474-81-8（普卡必利盐酸盐） 179474-81-8（普卡必利） | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | 5 HT Receptor/Serotonin Receptor | ||
结构式
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