MG101
| CAS No. | 110044-82-1 | Cat. No. | BCP28014 |
| Name | MG101 | ||
| Synonyms | Calpain Inhibitor I; MG-101; MG 101; ALLN; AcLLnLCHO; Ac-LLnL-CHO;Ac-Leu-Leu-Nle-Aldehyde;Acetylleucyl-leucyl-norleucinal; | ||
| Formula | C20H37N3O4 | M. Wt | 383.53 |
| Description | MG-101 is a calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Activities of MG-101 includes: (1) reduce colon injury caused by dinitrobenzene sulphonic acid; (2) overcome acquired resistance to TRAIL; (3) protect against atractyloside-induced toxicity. (4). reduce colon injury caused by dinitrobenzene sulphonic acid. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Proteasome | ||
Structure
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