依匹斯汀盐酸盐
| CAS号 | 80012-44-8 | 货号 | BCP09495 |
| 中文名 | 依匹斯汀盐酸盐 | ||
| 英文名 | Epinastine hydrochloride | ||
| 中文别名 | |||
| 英文别名 | Alesion; Elestat; Epinastine HCl; Epinastin HCl; | ||
| 分子式 | C16H16ClN3 | 分子量 | 285.77 |
| 生物活性 | Epinastine Hydrochloride is an histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors. | ||
| 信号通路 | Neuro Signaling Pathway GPCR/G Protein | ||
| 靶 点 | Histamine Receptor | ||
结构式
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