Cefuroxime Axetil

  • Chemical Properties
CAS No. 64544-07-6 Cat. No. BCP10740
Name Cefuroxime Axetil
Synonyms CCI 15641;CCI-15641;CCI15641;Ceftin; Zinnat; Elobact; Zinat; Cefuroxime 1-acetoxyethyl ester;
Formula C20H22N4O10S M. Wt 510.47
  • Biological Activity
Description Cefuroxime Axetil is a second generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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