Ceftezole

  • Chemical Properties
CAS No. 26973-24-0 Cat. No. BCP12070
Name Ceftezole
Synonyms Ceftezol; Ceftezolum;
Formula C13H12N8O4S3 M. Wt 440.48
  • Biological Activity
Description Ceftezole is a semisynthetic first-generation cephalosporin with antibacterial activity. Ceftezole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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