Dabigatran ethyl ester

  • Chemical Properties
CAS No. 429658-95-7 Cat. No. BCP12049
Name Dabigatran ethyl ester
Synonyms BIBR-951CL; BIBR 951CL; BIBR951CL;
Formula C27H29N7O3 M. Wt 499.56
  • Biological Activity
Description Dabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.
Pathways Protease/Metabolic Enzyme 
Targets Thrombin 

Structure

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