Guanfacine hydrochloride

  • Chemical Properties
CAS No. 29520-14-7 Cat. No. BCP28817
Name Guanfacine hydrochloride
Synonyms Guanfacine HCl;
Formula C9H9Cl2N3O M. Wt 246.09
  • Biological Activity
Description Guanfacine Hydrochloride is the hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Adrenergic Receptor 

Structure

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