BD1047dihydrobromide
| CAS No. | 138356-21-5 | Cat. No. | BCP15756 |
| Name | BD1047dihydrobromide | ||
| Synonyms | BD-1047 dihydrobromide;BD 1047dihydrobromide; BD-1047 2HBr; | ||
| Formula | C13H20Cl2N2.2HBr | M. Wt | 437.04 |
| Description | BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.BD1047 is a potent and selective Sigma-1 Receptor Antagonist. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Sigma Receptor | ||
Structure
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