氨己烯酸
| CAS号 | 60643-86-9 | 货号 | BCP16220 |
| 中文名 | 氨己烯酸 | ||
| 英文名 | Vigabatrin | ||
| 中文别名 | 氨已烯酸;4-氨基-5-己烯酸; | ||
| 英文别名 | gamma-vinyl-GABA;CPP109; CPP-109; CPP 109; RMI 71754; RMI71754; RMI-71754; MDL 71754; MDL-71754; MDL71754; | ||
| 分子式 | C6H11NO2 | 分子量 | 129.16 |
| 生物活性 | Vigabatrin is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. Vigabatrin is an irreversible suicide inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the catabolism of GABA, which increases the level of GABA in the brain. Vigabatrin is a racemic compound, and its [S]-enantiomer is pharmacologically active. | ||
| 信号通路 | Ion Channel/Membrane Transporter | ||
| 靶 点 | GABA Receptor | ||
结构式
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