Telotristat besilate

  • Chemical Properties
CAS No. 1374745-52-4 Cat. No. BCP16704
Name Telotristat besilate
Synonyms LP-778902 besilate; LP 778902 besilate; LP778902 besilate;
Formula C31H28ClF3N6O6S M. Wt 705.1
  • Biological Activity
Description Telotristat besilate is a tryptophan hydroxylase inhibitor.Telotristat, also known as LP-778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical- and infection-induced intestinal inflammation.
Pathways Protease/Metabolic Enzyme 
Targets Tryptophan Hydroxylase/TPH 

Structure

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