NFPS

  • Chemical Properties
CAS No. 405225-21-0 Cat. No. BCP17140
Name NFPS
Synonyms (±)-NFPS;
Formula C24H24FNO3 M. Wt 393.46
  • Biological Activity
Description NFPS is a selective non-transportable GlyT1 inhibitor.Selective, non-transportable inhibitor of GlyT1 which displays no activity at GABA or glutamate receptors (IC50 values are 2.8, 9.8 and 56000 nM for hGlyT1, rGlyT1 and rGlyT2 respectively). Enhances the amplitude of the NMDA component of glutamatergic EPSCs.
Pathways Ion Channel/Membrane Transporter 
Targets GlyT 

Structure

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