LIMKI-3
| CAS No. | 1338247-35-0 | Cat. No. | BCP17223 |
| Name | LIMKI-3 | ||
| Synonyms | LIMKI 3; LIMKI3; BMS-5; BMS 5; BMS5; | ||
| Formula | C17H14Cl2F2N4OS | M. Wt | 431.29 |
| Description | LIMKI-3, also known as BMS-3, is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | LIMK | ||
Structure
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