WZB117
| CAS No. | 1223397-11-2 | Cat. No. | BCP24665 |
| Name | WZB117 | ||
| Synonyms | WZB-117; WZB 117; | ||
| Formula | C20H13FO6 | M. Wt | 368.31 |
| Description | WZB117 is a potent Glut1 inhibitor. Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation. Blockade of GLUT1 by WZB117 resensitizes breast cancer cells to adriamycin. WZB117 is a prototype for further development of anticancer therapeutics targeting Glut1-mediated glucose transport and glucose metabolism | ||
| Pathways | GPCR/G Protein | ||
| Targets | Glucose Transporter | ||
Structure
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