CNDAC

  • Chemical Properties
CAS No. 135598-68-4 Cat. No. BCP24745
Name CNDAC
Synonyms TAS109; TAS109; TAS 109; DFP-10917; DFP 10917; DFP10917;
Formula C10H12N4O4 M. Wt 252.23
  • Biological Activity
Description CNDAC, also known as DFP-10917 and TAS-109, is an analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.
Pathways Cell Cycle/DNA Damage 
Targets Antimetabolite 

Structure

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