AFN-1252
| CAS No. | 620175-39-5 | Cat. No. | BCP19135 |
| Name | AFN-1252 | ||
| Synonyms | AFN 1252;AFN1252; AFN-12520000; API-1252; Debio-1452; AFN12520000; API1252; Debio1452; | ||
| Formula | C22H21N3O3 | M. Wt | 375.42 |
| Description | AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is an enoyl-(acyl-carrier protein) reductase fabl inhibitor potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 demonstrates a Staphylococcus-specific spectrum of activity. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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