NQ-301

  • Chemical Properties
CAS No. 130089-98-4 Cat. No. BCP24908
Name NQ-301
Synonyms NQ 301; NQ301;
Formula C18H12ClNO3 M. Wt 325.75
  • Biological Activity
Description NQ-301 is a Selective CD45 inhibitor with Antiplatelet and antithrombotic activities (IC50 = 200 nM). NQ301 inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. The antiplatelet activity of NQ301 may be mediated by inhibition of cytosolic Ca2+ mobilization, enhancement of cAMP production and inhibition of ATP secretion in activated platelets.
Pathways Protease/Metabolic Enzyme 
Targets Thrombin 

Structure

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