罗加替尼
| CAS号 | 1443530-05-9 | 货号 | BCP25142 |
| 中文名 | 罗加替尼 | ||
| 英文名 | Rogaratinib | ||
| 中文别名 | |||
| 英文别名 | BAY1163877; BAY-1163877; BAY 1163877; | ||
| 分子式 | C23H26N6O3S | 分子量 | 466.56 |
| 生物活性 | Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity. FGFRs are a family of receptor tyrosine kinases, which may be upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | FGFR | ||
结构式
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