Eritoran
| CAS No. | 185955-34-4 | Cat. No. | BCP25714 |
| Name | Eritoran | ||
| Synonyms | B-1287; B1287; B 1287; E 5564; E-5564; E5564; | ||
| Formula | C66H126N2O19P2 | M. Wt | 1313.66 |
| Description | Eritoran is a synthetic analogue of the lipid A portion of the endotoxin lipopolysaccharide (LPS) with potential immunomodulating activity. Eritoran binds to a receptor complex composed of toll-like receptor 4 (TLR4), CD14 and MD2 (MD-2, LY96) that is present on most cells of the immune system, inhibiting the activation of the receptor complex by LPS, which may result in the inhibition of pro-inflammatory cytokine secretion and a potentially fatal systemic inflammatory response syndrome (SIRS). LPS is found in the outer membrane of Gram-negative bacteria and binds to the TLR4/CD14/MD2 receptor complex of immune cells, including macrophages, resulting in the release of pro-inflammatory cytokines. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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