CEP-40783

  • Chemical Properties
CAS No. 1437321-24-8 Cat. No. BCP25839
Name CEP-40783
Synonyms CEP40783; CEP 40783; RXDX-106; RXDX 106; RXDX106;
Formula C31H26F2N4O6 M. Wt 588.56
  • Biological Activity
Description CEP-40783, also known as RXDX-106, is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively for use in breast, non-small cell lung (NSCLC), and pancreatic cancers.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets TAM Receptor c Met 

Structure

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