KN-93 hydrochloride

  • Chemical Properties
CAS No. 1956426-56-4 Cat. No. BCP25921
Name KN-93 hydrochloride
Synonyms KN-93 (HCI); KN-93 HCI; KN-93-HCI; KN93 (HCI); KN93 Hydrochloride; KN 93 Hydrochloride; KN-93(Hydrochloride);
Formula C26H30Cl2N2O4S M. Wt 537.49
  • Biological Activity
Description KN-93 hydrochloride is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.KN-93 is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK-II). It inhibits fibroblast CaMK-II activity and cell growth in a dose-dependent manner, reversibly arrests cells in G1 and induces apoptosis.
Pathways Neuro Signaling Pathway 
Targets CaMK 

Structure

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