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Chemical Structure Cat. No. Product Name CAS No.
Romifidine Chemical Structure
 BCP28726 Romifidine 65896-16-4
Romifidine is an α2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo.
Guanfacine hydrochloride Chemical Structure
 BCP28817 Guanfacine hydrochloride 29520-14-7
Guanfacine hydrochloride is a member of acetamides. It has a role as a geroprotector.
NS-11394 Chemical Structure
 BCP23679 NS-11394 951650-22-9
NS11394 is an orally active and unique subtype-selective GABAA positive allosteric receptor (PAM), with a Ki of ~0.5 nM. NS11394 shows a selectivity profile in the order of GABAA-5 > α3 > α2 > α1-containing receptors. NS11394 has anxiolytic and anti-inflammatory properties.
Dipraglurant Chemical Structure
 BCP23706 Dipraglurant 872363-17-2
Dipraglurant is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo.
L-733060 hydrochloride Chemical Structure
 BCP49092 L-733060 hydrochloride 148687-76-7
L-733,060 is an orally active, non-peptide, selective antagonist for the NK1 receptor with Ki of 0.8 nM.
MMPIP Chemical Structure
 BCP23933 MMPIP 479077-02-6
MMPIP is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM).
VU0364289 Chemical Structure
 BCP23956 VU0364289 1242443-29-3
VU0364289 is a novel N-aryl piperazine mGlu5 positive allosteric modulator.
ARL 14495 Chemical Structure
 BCP23970 ARL 14495 123319-03-9
ARL 14495 is a rigid M1/M3 muscarinic agonist affecting acetylcholine activity, used often in the treatment of Alzheimer’s disease.
AR-R17779 Chemical Structure
 BCP24016 AR-R17779 178419-47-1
AR-R17779 is a selective alpha7 nicotinic agonist (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively).
AF-353 hydrochloride Chemical Structure
 BCP24140 AF-353 hydrochloride 927887-18-1
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
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