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SARS CoV

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SARS CoV

Chemical Structure Cat. No. Product Name CAS No.
MERS-CoV-IN-1 Chemical Structure
 BCP46933 MERS-CoV-IN-1 2245697-92-9
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.
Ensitrelvir fumarate Chemical Structure
 BCP46193 Ensitrelvir fumarate 2757470-18-9
Ensitrelvir (S-217622) fumarate is the first orally active non-covalent, non-peptidic, SARS-CoV-2 3CL protease inhibitor (IC50=13 nM).
YH-53 Chemical Structure
 BCP45054 YH-53 1471484-62-4
YH-53 is a potent 3CL Protease inhibitor wit Ki values of 6.3 nM, 34.7 nM for SARS-CoV-1 3CL Protease and SARS-CoV-2 3CL Protease, respectively. YH-53 strongly blocks the SARS-CoV-2 replication.
GS-621763 Chemical Structure
 BCP45381 GS-621763 2647442-13-3
GS-621763, an orally bioavailable prodrug of GS-441524, shows antiviral activity against SARS-CoV-2 pathogenesis in mice.
SSAA09E2 Chemical Structure
 BCP43791 SSAA09E2 883944-52-3
SSAA09E2 is a novel inhibitor of SARS-CoV replication, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
AT-511 Chemical Structure
 BCP43134 AT-511 1998705-64-8
AT-511 is a prodrug form of the antiviral nucleoside analog AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 µM, respectively). AT-527 is the sulfate salt of AT-511.
Oxocarbazate Chemical Structure
 BCP42707 Oxocarbazate 1014405-03-8
Oxocarbazate is an inhibitor of human cathepsin L.
Merafloxacin Chemical Structure
 BCP42636 Merafloxacin 91188-00-0
Merafloxacin is a fluoroquinolone antibacterial, which was also identified as a −1 PRF inhibitor of SARS-CoV-2.
Decanoyl-arg-val-lys-arg-chloromethylketone Chemical Structure
 BCP41990 Decanoyl-arg-val-lys-arg-chloromethylketone 150113-99-8
Decanoyl-RVKR-CMK is a subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin).
SM-102 Chemical Structure
 BCP40910 SM-102 2089251-47-6
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles which is used in the Moderna COVID-19 vaccine.
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