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PKC

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PKC

Chemical Structure Cat. No. Product Name CAS No.
K-252B Chemical Structure
 BCP25306 K-252B 99570-78-2
K-252b, an indolocarbazole isolated from the actinomycete Nocardiopsis, is a PKC inhibitor.
Bisindoylmaleimide X HCl Chemical Structure
 BCP25394 Bisindoylmaleimide X HCl 145317-11-9
Bisindolylmaleimide X hydrochloride is a potent and selective protein kinase C (PKC) inhibitor.
H7 Chemical Structure
 BCP48822 H7 84477-87-2
H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC.
PKCiota-IN-2 Chemical Structure
 BCP48168 PKCiota-IN-2 2230055-52-2
PKCiota-IN-2 is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
H7 dihydrochloride Chemical Structure
 BCP47052 H7 dihydrochloride 108930-17-2
H-7 dihydrochloride is a protein kinase inhibitor (IC50 = 6.0, 5.8, 3.0 and 97.0 μM for inhibition of PKC, PKG, PKA and myosin light chain kinase, respectively).
Ruboxistaurin mesylate Chemical Structure
 BCP45743 Ruboxistaurin mesylate 192050-59-2
Ruboxistaurin mesylate is a orally active protein kinase C β (PKC-β) specific inhibitor; a salt form that is five times more water-soluble than its hydrochloride salt.
Bisindolylmaleimide VIII acetate Chemical Structure
 BCP43574 Bisindolylmaleimide VIII acetate 138516-31-1
Bisindolylmaleimide VIII acetate is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC.
Bisindolylmaleimide IV Chemical Structure
 BCP43512 Bisindolylmaleimide IV 119139-23-0
Bisindolylmaleimide IV is an inhibitor of pyruvate phosphate dikinase (PPDK).
D-erythro-Sphingosine HCl Chemical Structure
 BCP40404 D-erythro-Sphingosine HCl 2637-72-5
D-erythro-Sphingosine is an inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.
Phorbol 12,13-dibutyrate Chemical Structure
 BCP38374 Phorbol 12,13-dibutyrate 37558-16-0
Phorbol 12,13-dibutyrate is a PKC activator and a potent skin tumor promoter.
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