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Ferroptosis

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Ferroptosis

Chemical Structure Cat. No. Product Name CAS No.
Buthionine sulfoximine Chemical Structure
 BCP24029 Buthionine sulfoximine 5072-26-4
DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
SRS16-86 Chemical Structure
 BCP43520 SRS16-86 1793052-96-6
SRS16-86 is an inhibitor of ferroptosis. It inhibits ferroptosis induced by erastin in HT-1080 and NIH3T3 cells. SRS16-86 prevents renal tubular damage and increases in serum levels of urea and creatine in a mouse model of renal ischemia-reperfusion injury (IRI).
SRS11-92 Chemical Structure
 BCP41935 SRS11-92 1467047-25-1
SRS11-92 is a ferroptosis inhibitor and a derivative of ferrostatin-1.
iFSP1 Chemical Structure
 BCP37001 iFSP1 150651-39-1
iFSP1 is a ferroptosis suppressor protein 1 (FSP1) inhibitor and ferroptosis inducer.
Donafenib Chemical Structure
 BCP34023 Donafenib 1130115-44-4
Donafenib is an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases with potential anticancer acivity. Donafenib is under clinical trials in China in patients with advanced hepatocellular carcinoma (HCC).
Imidazole ketone erastin Chemical Structure
 BCP31858 Imidazole ketone erastin 1801530-11-9
Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications.
UAMC-3203 hydrochloride Chemical Structure
 BCP30942 UAMC-3203 hydrochloride 2271358-65-5
UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.
Tinoridine Chemical Structure
 BCP12825 Tinoridine 24237-54-5
Tinoridine, also known as Y-3642, is a non-steroidal anti-inflammatory drug.
Tinoridine hydrochloride Chemical Structure
 BCP30905 Tinoridine hydrochloride 25913-34-2
Tinoridine hydrochloride is a nonsteroidal anti-inflammatory drug and also has potent radical scavenger and antiperoxidative activity.
PF-06282999 Chemical Structure
 BCP20203 PF-06282999 1435467-37-0
PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.
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