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Estrogen Receptor

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Estrogen Receptor

Chemical Structure Cat. No. Product Name CAS No.
Methylpiperidino pyrazole Chemical Structure
BCP48025 Methylpiperidino pyrazole 289726-02-9
Methylpiperidino pyrazole is a high-affinity and selective ERα antagonist, exhibiting 200-fold potency for ERα over ERβ.
H3B-6545 Hydrochloride Chemical Structure
BCP48272 H3B-6545 Hydrochloride 2052132-51-9
H3B-6545 Hydrochloride is a selective, oral estrogen receptor covalent antagonist (SERCA).
2-Hydroxyestrone Chemical Structure
BCP46743 2-Hydroxyestrone 362-06-1
2-Hydroxyestrone, a specific receptor-mediated antiestrogenic agent with anticarcinogenic activity, inhibits the proliferation of estrogen receptor-positive MCF-7, but not estrogen receptor-negative MDA-MB-231.
ARV-471 Chemical Structure
BCP45881 ARV-471 2229711-08-2
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader.
Amcenestrant Chemical Structure
BCP38455 Amcenestrant 2114339-57-8
Amcenestrant (SAR439859) is an orally available and nonsteroidal selective estrogen receptor degrader (SERD) with potential antineoplastic activity. SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0.2 nM for ERα degradation.
Giredestrant tartrate Chemical Structure
BCP43932 Giredestrant tartrate 2407529-33-1
Giredestrant, also known as GDC-9545 and RG6171, is a SERD.
E3 ligase Ligand 5 Chemical Structure
BCP42856 E3 ligase Ligand 5 1055361-35-7
E3 ligase Ligand 5 is an estrogen-related receptor α (ERRα) antagonist with IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively.
PPT Chemical Structure
BCP41931 PPT 263717-53-9
PPT, also known as Propyl pyrazole triol, is an estrogen receptor (ERalpha) agonist. PPT also exerts anti-diabetic effects in mouse models.
Giredestrant Chemical Structure
BCP39883 Giredestrant 1953133-47-5
Giredestrant is a SERD.
trans-Clomifene Citrate Chemical Structure
BCP41267 trans-Clomifene Citrate 7599-79-3
trans-Clomiphene a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function.
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