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CDK

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CDK

Chemical Structure Cat. No. Product Name CAS No.
SRX3177 Chemical Structure
 BCP48567 SRX3177 2241237-51-2
SRX3177 is a novel potent triple action inhibitor, targeting BRD, PI3K, and CDK.
GSK-3/CDK5/CDK2-IN-1 Chemical Structure
 BCP48519 GSK-3/CDK5/CDK2-IN-1 395074-72-3
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a.
HQ461 Chemical Structure
 BCP47151 HQ461 1226443-41-9
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation.
Cdk2/9 Inhibitor Chemical Structure
 BCP46934 Cdk2/9 Inhibitor 507487-89-0
Cdk2/9 Inhibitor is a small molecule/inhibitor primarily used for phosphorylation and dephosphorylation applications.
Aminopurvalanol A Chemical Structure
 BCP46783 Aminopurvalanol A 220792-57-4
Aminopurvalanol A selectively inhibits TgCK1alpha. Aminopurvalanol A also acts as a cell-permeable cyclin-dependent kinase inhibitor, inhibiting cdk1/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5/p35.
GTAEXS-617 Chemical Structure
 BCP46568 GTAEXS-617 GTAEXS-617
GTAEXS-617 is a selective and highly potent inhibitor of CDK7.
CDK12-IN-2 Chemical Structure
 BCP46385 CDK12-IN-2 2244987-03-7
CDK12-IN-2 is a potent, selective and nanomolar CDK12 inhibitor (IC50=52 nM) with good physicochemical properties.
CAY10574 Chemical Structure
 BCP46439 CAY10574 140651-18-9
CAY10574(Cdk9 Inhibitor II,CAN508) is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. Antitumor activity.
M2N12 Chemical Structure
 BCP46438 M2N12 2376577-06-7
M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhibitor with an IC50 value of 0.09  μM.
CDK4/6-IN-6 Chemical Structure
 BCP46270 CDK4/6-IN-6 2380321-51-5
CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
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