Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Neurotensin Receptor
- Melatonin Receptor
- Urotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Somatostatin Receptor
- Adenylate Cyclase
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- Adenosine Receptor
- OX Receptor
- Prostaglandin Receptor
- Glucagon Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- mAChR
- P2 Receptor
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Opioid Receptor
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Monoamine Oxidase
- Imidazoline Receptor
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- mGluR
- Histamine Receptor
- Adrenergic Receptor
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- nAChR
- CGRP Receptor
- FAAH
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- Xanthine Oxidase
- Mitochondrial Metabolism
- ACC
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
- CETP
- Neprilysin
- MAGL
- MLR
- FTase
- Carbonic Anhydrase
- Elastase
- E1 E2 E3 Enzyme
- PAI1
- ROR
- NOX
- Glucokinase
- Aldose Reductase
- FAS
- Tyrosinase
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HSP
- HCV Protease
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Diabetes
- Endocrinology
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Indazole Series
- Piperidine Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
EGFR
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
![]() |
BCP44759 | Amphiregulin, Human Recombinant New | 117147-70-3 |
Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts.
|
![]() |
BCP44623 | Almonertinib hydrochloride New | 2134096-03-8 |
Almonertinib hydrochloride is an orally available and third-Generation inhibitor of epidermal growth factor receptor (EGFR)-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
|
![]() |
BCP44108 | PF-06459988 New | 1428774-45-1 |
PF-06459988 is an orally available, small molecule, third-generation, irreversible inhibitor of epidermal growth factor receptor (EGFR) mutant (EGFRm) forms with potential antineoplastic activity.
|
![]() |
BCP43207 | AZ7550 hydrochloride New | 2309762-40-9 |
AZ-7550 is a metabolite of Osimertinib.
|
![]() |
BCP39664 | AST5902 New | AST5902 |
Alflutinib is mainly metabolized via CYP3A4 to form its active metabolite AST5902.
|
![]() |
BCP38649 | JND3229 New | 2260886-64-2 |
JND3229 is a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy (IC50 = 5.8 nM).
|
![]() |
BCP38312 | Almonertinib New | 1899921-05-1 |
Almonertinib is an EGFR tyrosine kinase inhibitor. Upon administration, HS-10296 binds to and inhibits EGFR T790M, a secondarily acquired resistance mutation, inhibits the tyrosine kinase activity of EGFR T790M, prevents EGFR T790M-mediated signaling and leads to cell death in EGFR T790M-expressing tumor cells.
|
![]() |
BCP37982 | Epertinib hydrochloride New | 2071195-74-7 |
Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4. It shows potent antitumor activity.
|
![]() |
BCP37896 | TX1-85-1 New | 1603845-32-4 |
TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM).
|
![]() |
BCP37851 | PD089828 New | 179343-17-0 |
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity.
|
