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FLT3

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FLT3

Chemical Structure Cat. No. Product Name CAS No.
KG5 Chemical Structure
 BCP46930 KG5 877874-85-6
KG 5 is an orally available PDGFRß and B-Raf allosteric inhibitor.
MAX-40279 hemifumarate Chemical Structure
 BCP46381 MAX-40279 hemifumarate 2388506-43-0
MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase.
MAX-40279 hemiadipate Chemical Structure
 BCP46003 MAX-40279 hemiadipate 2388506-44-1
MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase.
MAX-40279 Chemical Structure
 BCP46002 MAX-40279 2070931-57-4
MAX-40279 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) and FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2), with potential antineoplastic activity.
FLT3-IN-3 Chemical Structure
 BCP45355 FLT3-IN-3 2229050-90-0
FLT3-IN-3 is a potent and selective FLT3 inhibitor.
HM43239 Chemical Structure
 BCP40967 HM43239 2569527-64-4
HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations.
SB1317 Chemical Structure
 BCP42651 SB1317 1204918-72-8
SB1317 is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
CA-4948 Chemical Structure
 BCP33271 CA-4948 1801344-14-8
CA-4948 is a potent IRAK4/FLT3 inhibtor with anti-tumor activity.
UNC2025 hydrochloride Chemical Structure
 BCP36467 UNC2025 hydrochloride 2070015-17-5
UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor.
TG-89 Chemical Structure
 BCP35054 TG-89 936091-56-4
TG-89 is an inhibitor of JAK2, FLT3, RET and JAK3.
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