Home   >  
GPCR/G Protein
Sigma Receptor

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products






Raw Materials

Sigma Receptor

Chemical Structure Cat. No. Product Name CAS No.
NE 100 hydrochloride Chemical Structure
BCP23907 NE 100 hydrochloride 149409-57-4
NE 100 is a potent and selective σ1 receptor antagonist (Ki = 0.86 nM) that displays > 55-fold selectivity over σ2 receptors and > 6000-fold selectivity over D1, D2, 5-HT1A, 5-HT2 and PCP receptors. Exhibits reversible binding (Kd = 1.2 nM) and displays antipsychotic activity in vivo. Orally active.
WQ 1 Chemical Structure
BCP46446 WQ 1 1204401-49-9
WQ 1 is a high affinity and selective σ1 receptor antagonist. It displays σ1/σ2 selectivity ratio of 29512. It Selectively blocks binge eating without a general inhibition of food intake in rats.
Sigma-1 receptor antagonist 2 Chemical Structure
BCP46031 Sigma-1 receptor antagonist 2 1639220-15-7
Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively.
Roluperidone Chemical Structure
BCP45266 Roluperidone 359625-79-9
Roluperidone is a 5-HT2A and sigma 2 receptor antagonist potentially for the treatment of schizophrenia.
Rimcazole dihydrochloride Chemical Structure
BCP44459 Rimcazole dihydrochloride 75859-03-9
Rimcazole dihydrochloride is a small molecule antagonist of the σ-1 receptor and inhibits tumor cell survival.
EST64454 HCl Chemical Structure
BCP43797 EST64454 HCl 1950569-11-5
EST64454 is a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management.
SR 31747 Chemical Structure
BCP35688 SR 31747 132173-07-0
SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase.
BD 1047 Chemical Structure
BCP33959 BD 1047 138356-20-4
BD-1047 is a selective functional antagonist of sigma-1 receptor, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.
Cutamesine Chemical Structure
BCP32724 Cutamesine 165377-43-5
Cutamesine (SA4503; AGY-94806) is a selective sigma 1 receptor(σ1R) agonist; high affinity for the sigma 1 receptor subtype labeled by (+)-[3H]pentazocine (IC50= 17.4±1.9 nM); 100-fold less affinity for the sigma 2 receptor.
BD1063 dhydrochloride Chemical Structure
BCP31637 BD1063 dhydrochloride 206996-13-6
BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
123下一页共 26 条记录 1 / 3 页