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Beta catenin

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Beta catenin

Chemical Structure Cat. No. Product Name CAS No.
LF3 Chemical Structure
BCP45492 LF3 664969-54-4
LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM.
β-catenin/CBP-IN-1 Chemical Structure
BCP44122 β-catenin/CBP-IN-1 1198780-38-9
β-catenin/CBP-IN-1 (CBP/β-catenin inhibitor) is a potent and selective CBP/β-catenin inhibitor, extracted from the patent WO2014092154A1.
IWP-4 Chemical Structure
BCP43694 IWP-4 686772-17-8
IWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling.
CWP232228 sodium Chemical Structure
BCP43357 CWP232228 sodium 1144044-02-9
CWP232228 is a novel Wnt/β-Catenin inhibitor.
G244-LM Chemical Structure
BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
NRX-252262 Chemical Structure
BCP36626 NRX-252262 2438637-61-5
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.
C-82 Chemical Structure
BCP35612 C-82 1422253-37-9
C-82 is a second-generation specific CBP/β-catenin antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
KY1220 Chemical Structure
BCP34008 KY1220 292168-79-7
KY1220 is a small molecule that simultaneously degrades β-catenin and Ras by inhibition of the Wnt/β-catenin pathway.
Tegatrabetan Chemical Structure
BCP32893 Tegatrabetan 1227637-23-1
Tegatrabetan is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1).
WIKI4 Chemical Structure
BCP15357 WIKI4 838818-26-1
WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
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