Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Neurotensin Receptor
- Melatonin Receptor
- Urotensin Receptor
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- Microbiology/Virology
-
Neuro Signaling Pathway
- Monoamine Oxidase
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- Beta secretase
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- SSRI
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- P glycoprotein
- Opioid Receptor
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- mGluR
- Histamine Receptor
- Adrenergic Receptor
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- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- nAChR
- CGRP Receptor
- FAAH
- COX
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- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
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- Mitochondrial Metabolism
- ACC
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
- CETP
- Neprilysin
- MAGL
- MLR
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- Carbonic Anhydrase
- Elastase
- E1 E2 E3 Enzyme
- PAI1
- ROR
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- Glucokinase
- Aldose Reductase
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- Tyrosinase
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
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- Phosphatase
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- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
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- Aminopeptidase
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- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Diabetes
- Endocrinology
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Indazole Series
- Piperidine Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
PAK
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP42390 | IPA-3 New | 42521-82-4 |
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).
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BCP31326 | beta-Elemene New | 33880-83-0 |
beta-Elemene is an inhibitor of Pak1 activation, and an anti-cancer ingredient isolated from the Chinese traditional herb Curcuma wenyujin.
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BCP31238 | FTY720 Acetic Acid Hydrochloride New | 1346598-36-4 |
FTY720 is a sphingosine 1-phosphate (S1P) antagonist with IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
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BCP10637 | KPT9274 | 1643913-93-2 |
PAK4-IN-1 is an inhibitor of p21-activated kinases (PAKs), with IC50 of ≤100 nM in MTT assay.
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BCP29548 | NVS-PAK1-1 | 1783816-74-9 |
NVS-PAK1-1 is a a specific allosteric PAK1 inhibitor.
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BCP12649 | FRAX597 | 1286739-19-2 |
FRAX597, a small-molecule pyridopyrimidinone, is a potent and ATP competitive inhibitor of the group I PAKs (PAK1 IC50= 8 nM, PAK2 IC50= 13 nM, PAK3 IC50= 19 nM).
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BCP20209 | FRAX-1036 | 1432908-05-8 |
FRAX1036 is a novel ATP-competitive small molecule inhibitor of group I p21-activated Kinases (PAKs).
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BCP05326 | 5-Aminosalicylic acid New | 89-57-6 |
5-Aminosalicylic acid is an anti-inflammatory compound.
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BCP13764 | FRAX486 | 1232030-35-1 |
FRAX486 is a selective inhibitor of group I PAKs with IC50s of 8.25/39.5, /55.3 nM for PAK1/PAK2/PAK3 respectivelt; less potent for PAK4(IC50=779 nM).
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BCP05969 | Fingolimod | 162359-55-9 |
Fingolimod(FTY720 free base) is a S1P antagonist with IC50 of 0.033 nM.
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