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GPCR/G Protein

Chemical Structure Cat. No. Product Name CAS No.
TDI-10229 Chemical Structure
 BCP44963 TDI-10229 TDI-10229
TDI-10229 is a potent and orally bioavailable inhibitor of soluble adenylyl cyclase (sAC, ADCY10).
KRAS G12D inhibitor 5 Chemical Structure
 BCP44856 KRAS G12D inhibitor 5 2621928-53-6
KRAS G12D inhibitor 5 is a KRAS G12D inhibitor for the potential treatment of pancreatic cancer.
RTICBM-189 Chemical Structure
 BCP44866 RTICBM-189 551909-15-0
RTICBM-189 is a Urea derivative and a CB1 allosteric modulator.
Difelikefalin TFA Chemical Structure
 BCP44865 Difelikefalin TFA 2742623-88-5
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM).
CCR3 Antagonist Chemical Structure
 BCP44858 CCR3 Antagonist 275812-32-3
KRAS G12D inhibitor 1 Chemical Structure
 BCP43765 KRAS G12D inhibitor 1 2621928-43-4
KRAS G12D inhibitor 1 is a KRAS G12D inhibitor, with an IC50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation.
MRTX849 acid Chemical Structure
 BCP44575 MRTX849 acid 2561529-96-0
MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2.
MRTX849 analog 24 Chemical Structure
 BCP44576 MRTX849 analog 24 2490716-96-4
MRTX849 analog 24 is an alkyne-containing click probe analogue of KRAS G12C inhibitor MRTX849, which is used to research MRTX849 function.
CL 316243 Chemical Structure
 BCP44544 CL 316243 138908-40-4
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
U-54494A Chemical Structure
 BCP44497 U-54494A 92953-41-8
U-54494A is a κ-opioid agonist and a potential NMDA antagonist. U-54494A hydrochloride is used as an anticonvulsant.
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