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Signaling Pathways
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
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Research Areas
- Metabolic Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Pyridazine Series
- Ammonia Series
- Amino acid
- Nucleoside Series
- Azaindazole
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrrole Series
- Boric acid
- Pyrimidine Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
Ion Channel/Membrane Transporter
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP49138 | TRPV4 agonist-1 New | 2314467-59-7 |
TRPV4 agonist-1 free base is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay.
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BCP49136 | TRPV4 agonist-1 New | 2314467-60-0 |
TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay.
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BCP28391 | AF353 New | 865305-30-2 |
AF-353 is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.
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BCP49110 | Phlorizin dihydrate New | 7061-54-3 |
Phlorizin dihydrate can significantly inhibit oxidative DNA damage.
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BCP23679 | NS-11394 New | 951650-22-9 |
NS11394 is an orally active and unique subtype-selective GABAA positive allosteric receptor (PAM), with a Ki of ~0.5 nM. NS11394 shows a selectivity profile in the order of GABAA-5 > α3 > α2 > α1-containing receptors. NS11394 has anxiolytic and anti-inflammatory properties.
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BCP23781 | AR-C117977 New | 216685-07-3 |
AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance.
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BCP24016 | AR-R17779 New | 178419-47-1 |
AR-R17779 is a selective alpha7 nicotinic agonist (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively).
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BCP24140 | AF-353 hydrochloride New | 927887-18-1 |
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
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BCP24265 | Perampanel 3/4 hydrate New | 1571982-04-1 |
Perampanel hydrate is a hydrate obtained by combining four molecules of perampanel with three molecules of water. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.
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BCP24317 | Suloctidil New | 54767-75-8 |
Suloctidil is a new drug that is currently being evaluated in many clinical trials for use in dementia and thrombotic disorders Target: Effect of suloctidil on Na+/K+ ATPase activity and on membrane fluidity in rat brain synaptosomes.
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