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Ion Channel/Membrane Transporter

Chemical Structure Cat. No. Product Name CAS No.
TRPV4 agonist-1 Chemical Structure
BCP49138 TRPV4 agonist-1 2314467-59-7
TRPV4 agonist-1 free base is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay.
TRPV4 agonist-1 Chemical Structure
BCP49136 TRPV4 agonist-1 2314467-60-0
TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay.
AF353 Chemical Structure
BCP28391 AF353 865305-30-2
AF-353 is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3.
Phlorizin dihydrate Chemical Structure
BCP49110 Phlorizin dihydrate 7061-54-3
Phlorizin dihydrate can significantly inhibit oxidative DNA damage.
NS-11394 Chemical Structure
BCP23679 NS-11394 951650-22-9
NS11394 is an orally active and unique subtype-selective GABAA positive allosteric receptor (PAM), with a Ki of ~0.5 nM. NS11394 shows a selectivity profile in the order of GABAA-5 > α3 > α2 > α1-containing receptors. NS11394 has anxiolytic and anti-inflammatory properties.
AR-C117977 Chemical Structure
BCP23781 AR-C117977 216685-07-3
AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance.
AR-R17779 Chemical Structure
BCP24016 AR-R17779 178419-47-1
AR-R17779 is a selective alpha7 nicotinic agonist (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively).
AF-353 hydrochloride Chemical Structure
BCP24140 AF-353 hydrochloride 927887-18-1
AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively).
Perampanel 3/4 hydrate Chemical Structure
BCP24265 Perampanel 3/4 hydrate 1571982-04-1
Perampanel hydrate is a hydrate obtained by combining four molecules of perampanel with three molecules of water. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.
Suloctidil Chemical Structure
BCP24317 Suloctidil 54767-75-8
Suloctidil is a new drug that is currently being evaluated in many clinical trials for use in dementia and thrombotic disorders Target: Effect of suloctidil on Na+/K+ ATPase activity and on membrane fluidity in rat brain synaptosomes.
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