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Factor Xa

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Factor Xa

Chemical Structure Cat. No. Product Name CAS No.
Darexaban Chemical Structure
 BCP45981 Darexaban 365462-23-3
Darexaban is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC50 of 54.6 nM. Darexaban shows high selectivity against other related serine proteases, such as trypsin, thrombin, and kallikrein. Darexaban has anticoagulant and antithrombotic effects.
BMS-262084 Chemical Structure
 BCP45717 BMS-262084 253174-92-4
BMS 262084 is a potent and selective azetidinone-based beta-lactam tryptase inhibitor.
Edoxaban Chemical Structure
 BCP38288 Edoxaban 912273-65-5
Edoxaban is an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent has an elimination half-life of 9-11 hours and undergoes renal excretion.
BMS-962212 Chemical Structure
 BCP31167 BMS-962212 1430114-34-3
BMS-962212 is a reversible, direct, and highly selective inhibitor of FXIa.
BMS-740808 Chemical Structure
 BCP23400 BMS-740808 280118-23-2
BMS-740808 is a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
Betrixaban maleate Chemical Structure
 BCP25697 Betrixaban maleate 936539-80-9
Betrixaban is a highly potent, selective, and orally efficacious factor Xa inhibitor with IC50 of 1.2 nM(inhibition of Factor 10a).
Idraparinux sodium Chemical Structure
 BCP16293 Idraparinux sodium 149920-56-9
Idraparinux selectively blocks coagulation factor Xa.
Z-D-Arg-Gly-Arg-pNA 2 HCl Chemical Structure
 BCP18446 Z-D-Arg-Gly-Arg-pNA 2 HCl 113711-77-6
Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa.
Letaxaban Chemical Structure
 BCP24734 Letaxaban 870262-90-1
Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative.
D-PHE-PIP-ARG-PNA Chemical Structure
 BCP18445 D-PHE-PIP-ARG-PNA 115388-96-0
Thrombin substrates are often cleaved as well by trypsin and trypsin-like enzymes, e.g. I-1365, I-1560, J-1120, and L-1150. Chromogenic substrate specific for thrombin but insensitive to factor Xa.
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