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mAChR

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mAChR

Chemical Structure Cat. No. Product Name CAS No.
Diphemanil Methylsulfate Chemical Structure
 BCP44336 Diphemanil Methylsulfate 62-97-5
Diphemanil Methylsulfate is a quaternary ammonium anticholinergic.It binds muscarinic acetycholine receptors (mAchR).
Nebracetam Chemical Structure
 BCP44037 Nebracetam 116041-13-5
Nebracetam, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration.
Sofpironium bromide Chemical Structure
 BCP43183 Sofpironium bromide 1628106-94-4
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes.
VU0453595 Chemical Structure
 BCP43186 VU0453595 1432436-13-9
VU0453595 is a novel M1 positive allosteric modulator (PAM), potential in schizophrenia.
Scopolamine hydrobromide trihydrate Chemical Structure
 BCP40860 Scopolamine hydrobromide trihydrate 6533-68-2
Scopolamine is a competitive muscarinic acetylcholine receptor antagonist with IC50 value of 55.3 nM.
JHU37160 Chemical Structure
 BCP40726 JHU37160 2369979-68-8
JHU37160 exhibits high in vivo DREADD occupancy and was not reported to be a P-gp substrate.
JHU37152 Chemical Structure
 BCP40725 JHU37152 2369979-67-7
JHU37152 exhibits high in vivo DREADD occupancy and was not reported to be a P-gp substrate.
Anisodamine hydrobromide Chemical Structure
 BCP40337 Anisodamine hydrobromide 55449-49-5
Anisodamine is a naturally occurring atropine derivative, which is also known as 7β-hydroxyhyoscyamine. It is an anticholinergic and α1-adrenergic receptor as well as mAChR antagonist used in the treatment of acute circulatory shock in China.
DREADD agonist 21 Chemical Structure
 BCP34512 DREADD agonist 21 56296-18-5
DREADD agonist 21 has been found to be an agonist of hM3Dq with high selectivity.
Methscopolamine Chemical Structure
 BCP34407 Methscopolamine 13265-10-6
Methscopolamine is an Anticholinergic. The mechanism of action of methscopolamine is as a Cholinergic Antagonist.
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