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Chemical Structure Cat. No. Product Name CAS No.
ARL 14495 Chemical Structure
BCP23970 ARL 14495 123319-03-9
ARL 14495 is a rigid M1/M3 muscarinic agonist affecting acetylcholine activity, used often in the treatment of Alzheimer’s disease.
Otenzepad Chemical Structure
BCP24273 Otenzepad 100158-38-1
Otenzepad is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.
4-DAMP Chemical Structure
BCP49007 4-DAMP 1952-15-4
4-DAMP is a potent antagonist of M3 receptor and also has a high affinity for the closely-related M5 receptor.
Emraclidine Chemical Structure
BCP48520 Emraclidine 2170722-84-4
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator.
VU0467154 Chemical Structure
BCP47001 VU0467154 1451993-15-9
VU0467154 is a potent and selective M4 PAM. VU0467154 exhibits robust APD-like and cognitive enhancing activity in rodents. Selective M4 PAMs could provide a therapeutic strategy for the treatment of HD.
Deschloroclozapine Chemical Structure
BCP46891 Deschloroclozapine 1977-07-7
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging.
Diphemanil Methylsulfate Chemical Structure
BCP44336 Diphemanil Methylsulfate 62-97-5
Diphemanil Methylsulfate is a quaternary ammonium anticholinergic.It binds muscarinic acetycholine receptors (mAchR).
Nebracetam Chemical Structure
BCP44037 Nebracetam 116041-13-5
Nebracetam, a nootropic M1-muscarinic agonist, induces a rise of intracellular Ca2+ concentration.
Sofpironium bromide Chemical Structure
BCP43183 Sofpironium bromide 1628106-94-4
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes.
VU0453595 Chemical Structure
BCP43186 VU0453595 1432436-13-9
VU0453595 is a novel M1 positive allosteric modulator (PAM), potential in schizophrenia.
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